Publications
2026
Schmitter M, Hartmann L, Kedrov A (2026) Crowding at the cellular membranes: Emerging physiological roles and novel study approaches. Curr Opin Struct Biol 100, 103335.
Busch M*, Rosales-Hernandez C*, Kamel M*, Schaumkessel Y, van der Sluis EO, Berninghausen O, Becker T, Beckmann R & Kedrov A (2026) Substrate-induced assembly and fucntional mechanism of the bacterial membrane protein insertase SecYEG-YidC. EMBO J 45, 5457-5481.
Busch M*, Loschwitz J*, Papadopoulos A*, Reiners J, Steinchen W, Calvagna V, Smits SHJ, Jaeger KE & Kedrov A (2026) Conformational dynamics of the membrane-anchored foldase LipH from Pseudomonas aeruginosa governs recognition and release of its client lipase. J Biol Chem 302, 113266.
2025
Knospe CV, Ortiz J, Reiners J, Kedrov A, Gertzen CGW, Smits SHJ & Schmitt L (2025) Structural insights into the substrate binding mechanism of the class I dehydratase MadB. Commun Biol 8, 1032.
Benedens M*, Rosales-Hernandez C*, Straathof SAP, Loschwitz J, Berninghausen O, Maglia G, Beckmann R & Kedrov A (2025) Assembly and the gating mechanism of the Pel exopolysaccharide export complex PelBC of Pseudomonas aeruginosa. Nature Comms 5249.
Dali S, Schultz M, Köster M, Kamel M, Busch M, Steinchen W, Hänsch S, Papadopoulos A, Reiners J, Smits SHJ, Kedrov A, Altegoer F & Schipper K (2025) Specific phosphoinositide interactions of Jps1 is a key feature during unconventional secretion in Ustilago maydis. J Biol Chem 301, 110215.
2023
Löwe M, Hänsch S, Hachani E, Schmitt L, Weidtkamp-Peters S & Kedrov A (2023) Probing macromolecular crowding at the lipid membrane interface with genetically-encoded sensors. Protein Sci 32, e4797
Bonda L, Müller J, Fischer L, Löwe M, Kedrov A, Schmidt S & Hartmann L (2023) Facile Synthesis of Catechol-Containing Polyacrylamide Copolymers: Synergistic Effects of Amine, Amide and Catechol Residues in Mussel-Inspired Adhesives. Polymers 13, 3663.
Knospe CV, Kamel M, Spitz O, Hoeppner A, Galle S, Reiners J, Kedrov A, Smits SHJ & Schmitt L (2023) The structure of MadC from Clostridium maddingley reveals new insights into class I lanthipeptide cyclases. Front Microbiol 13, 1057217.
2022
Papadopoulos A, Busch M, Reiners J, Hachani E, Baeumers M, Berger J, Schmitt L, Jaeger KE, Kovacic F, Smits SHJ & Kedrov A (2022) The periplasmic chaperone Skp prevents misfolding of the secretory lipase A from Pseudomonas aeruginosa. Front Mol Biosci 9, 1026724.
2021
Weiler A, Spitz O, Gudzhuhn M, Schott-Verdugo S, Kamel M, Thiele B, Streit WR, Kedrov A, Scmitt L, Gohlke H & Kovacic F (2021) Novel intracellular phospholipase B from Pseudomonas aeruginosa with activity towards endogenous phospholipids affects biofilm assembly. Biochem Biophys Acta 1867, 159101.
Kamel M, Löwe M, Schott-Verdugo S, Gohlke H & Kedrov A (2021) Unsaturated fatty acids augment protein transport via the SecA:SecYEG translocon. FEBS J 289, 140-162.
Koch S, Seien A.-B, Kamel M, Kuckla D, Monzel C, Kedrov A & Driessen AJ (2021) Single-molecule observation of dynamics and interactions of the SecYEG translocon. FEBS J 228, 2203-2221.
2020 and earlier
Löwe M, Kalacheva M, Boersma AJ & Kedrov A (2020) The more the merrier: effects of macromolecular crowding on the structure and dynamics of biological membranes. FEBS J 287, 5039-5067.
Kater L, Frieg B, Berninghausen O, Gohlke H, Beckmann R & Kedrov A (2019) Partially inserted nascent chain unzips the lateral gate of the Sec translocon. EMBO Rep, e48191.
*Commented in: Tanaka & Tsukazaki (2019) A snapshot of membrane protein insertion. EMBO Reports, e49034
Kanonenberg K, Royes J, Kedrov A, Poschmann G, Angius F, Solgadi A, Spitz O, Kleinschrodt D, Stühler K, Miroux B & Schmitt L (2019) Shaping the lipid composition of bacterial membranes for membrane protein production. Microbial Cell Factories, 18, 31.
Löwe M, Papadopoulos A, Kamel M & Kedrov A (2019) Membranproteinfaltung - Kernwissen aus (nicht zu) vereinfachten Systemen. BIOspektrum, 25, 385-7.
Koch S, Driessen AJ & Kedrov A (2018) Biophysical analysis of Sec-mediated protein translocation in nanodiscs. Advances in Biomembranes and Lipid Self-Assembly, vol. 28, 41-85.